![(+)-(3r,5s), Tert-Butyl 7-[4-(4-Fluorophenyl)-6-Isopropyl-2-(N-Methyl-N-Methylsulphonylamino)-Pyrimidin-5-Yl]-3,5 -Dihydroxy-6(E)-Heptenate (R1.5 Utawa T-Butyl-Rosuvastatin) CAS: 355806-00-7 Gambar Unggulan](http://cdn.globalso.com/xdbiochems/白色粉末1133.jpg)
![(+)-(3r,5s), Tert-Butyl 7-[4-(4-Fluorophenyl)-6-Isopropyl-2-(N-Methyl-N-Methylsulphonylamino)-Pyrimidin-5-Yl]-3,5 -Dihydroxy-6(E)-Heptenate (R1.5 Utawa T-Butyl-Rosuvastatin) CAS: 355806-00-7](http://cdn.globalso.com/xdbiochems/粉末245.jpg)
(+)-(3r,5s), Tert-Butyl 7-[4-(4-Fluorophenyl)-6-Isopropyl-2-(N-Methyl-N-Methylsulphonylamino)-Pyrimidin-5-Yl]-3,5 -Dihydroxy-6(E)-Heptenate (R1.5 Utawa T-Butyl-Rosuvastatin) CAS: 355806-00-7
| Nomer Katalog | XD93420 |
| Jeneng produk | (+)-(3r,5s), Tert-Butyl 7-[4-(4-Fluorophenyl)-6-Isopropyl-2-(N-Methyl-N-Methylsulphonylamino)-Pyrimidin-5-Yl]-3,5 -Dihydroxy-6(E)-Heptenate (R1.5 utawa T-Butyl-Rosuvastatin) |
| CAS | 355806-00-7 |
| Formulir Molekulla | C26H36FN3O6S |
| Bobot Molekul | 537.64 |
| Rincian panyimpenan | Ambient |
Spesifikasi Produk
| Penampilan | Wêdakakêna putih |
| Assay | 99% min |
(+)-(3R,5S), tert-Butil 7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-metil-N-metilsulfonilamino)-pirimidin-5-yl]-3,5 -dihydroxy-6(E)-heptenate, uga dikenal minangka R1.5 utawa tert-butyl-rosuvastatin, minangka senyawa kimia sing bisa digunakake ing industri farmasi.Rosuvastatin minangka obat penurun kolesterol sing kondhang sing kalebu kelas saka obat-obatan sing diarani statin.Kerjane kanthi nyandhet enzim sing diarani HMG-CoA reductase, sing melu produksi kolesterol ing awak.R1.5 minangka turunan rosuvastatin sing ngemot gugus tert-butil sing ditempelake ing molekul kasebut, nyedhiyakake sifat tambahan lan keuntungan potensial.Salah sawijining aplikasi R1.5 sing bisa ditindakake yaiku minangka bahan farmasi kanggo perawatan hiperlipidemia lan nyegah penyakit kardiovaskular.Kaya rosuvastatin, R1.5 bisa digunakake kanggo ngedhunake tingkat kolesterol LDL, uga dikenal minangka kolesterol "ala", lan trigliserida ing getih.Senyawa iki bisa uga nuduhake sifat farmakokinetik sing luwih apik, kayata bioavailabilitas utawa stabilitas sing luwih apik, dibandhingake karo obat induk.Salajengipun, klompok tert-butil bisa nyumbang kanggo kelarutan senyawa lan versatility formulasi, nggawe cocok kanggo macem-macem sistem pangiriman tamba. Liyane potensial nggunakake R1.5 ing pangembangan prodrugs utawa diangkah sistem pangiriman tamba.Klompok tert-butil bisa tumindak minangka gugus protèktif, ngidini pelepasan rosuvastatin sing dikontrol ing jaringan utawa organ tartamtu, kayata ati.Strategi iki bisa ningkatake khasiat obat lan nyilikake efek samping potensial kanthi nambah konsentrasi ing situs target nalika ngurangi paparan jaringan non-target. Kajaba iku, R1.5 bisa dadi alat sing terkenal kanggo ahli kimia obat ing panemuan lan pangembangan obat.Struktur kompleks senyawa kasebut nyedhiyakake platform kanggo modifikasi lan derivatisasi luwih lanjut.Peneliti bisa nggunakake R1.5 minangka senyawa timbal kanggo njelajah hubungan struktur-aktivitas lan ngembangaken analog anyar karo nambah potency, selectivity, utawa profil terapeutik apik.Pasinaon kasebut bisa nyumbang kanggo pangembangan statin novel lan luwih efektif utawa agen penurun kolesterol liyane. -2-(N-methyl-N-methylsulphonylamino)-pyrimidin-5-yl]-3,5-dihydroxy-6(E)-heptenate (R1.5 utawa tert-butyl-rosuvastatin) nduweni janji minangka senyawa pharmaceutical kanggo perawatan hiperlipidemia lan penyakit kardiovaskular.Struktur unik, digabungake karo klompok tert-butil, bisa menehi kaluwihan kayata farmakokinetik sing luwih apik, pangiriman obat sing ditargetake, lan kesempatan kanggo pangembangan obat luwih lanjut.Riset lan pangembangan luwih akeh dibutuhake kanggo njelajah kanthi lengkap potensial R1.5 ing bidang farmasi.
